B6;129S5-Impa1tm1Lex/Ieg

Status

Available to order

EMMA IDEM:02319
International strain nameB6;129S5-Impa1tm1Lex/Ieg
Alternative nameLEXKO-374, PHO289N1
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolImpa1tm1Lex
Gene/Transgene symbolImpa1

Information from provider

Provider Lexicon Genetics, Inc.
Provider affiliationLexicon Pharmaceuticals
Phenotypic informationGenetic data indicate that this mutation resulted in greatly reduced viability of the homozygous mutants. All of the homozygous mutant mice died by 3 weeks of age. No notable phenotype was observed for the heterozygous mice. Disruption of the target gene was confirmed by Southern hybridization analysis.
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Disease and phenotype information

MGI phenotypes (allele matching)
  • hyperactivity / MGI
  • increased vertical activity / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • nervous system phenotype / MGI
  • increased vertical stereotypic behavior / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI
MGI phenotypes (gene matching)
  • hyperactivity / MGI
  • increased vertical activity / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • nervous system phenotype / MGI
  • increased vertical stereotypic behavior / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).