Systemic Phenotyping

The phenotypic analysis of genetically modified mouse models in a systemic, multi-organ approach has become a crucial tool for modern genetics research. INFRAFRONTIER partner institutes are world leaders in systemic phenotyping – and they offer the access to their data, their modern facilities, and their outstanding scientific expertise to all interested research partners in the scientific community.
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INFRAFRONTIER Systemic Phenotyping Service

First described by Gailus-Durner et al. (2009) Gailus-Durner et al. (2009, systemic phenotyping is a broad screening pipeline where mice are analysed systematically covering a wide range of tests to identify novel phenotypes. In other words, it is the systematic analysis of mutant mice through a standardised phenotyping pipeline across a range of biological systems. This type of phenotyping is carried out in mouse clinics within the INFRAFRONTIER consortium and requires large-scale capacity, broad expertise, specific equipment, and dedicated infrastructure.

Systemic phenotyping includes the analysis of:

Energy & Metabolism
Nervous System
Muscles & Bones
Cardiovascular System
Blood Chemistry
Reproductive System
Immune System

This page is still being worked on and will be updated regularly

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