The European Mouse Mutant Archive – EMMA
The European Mouse Mutant Archive – EMMA is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse and rat strains essential for basic biomedical research. The laboratory mouse is the most important mammalian model for studying genetic and multi-factorial diseases in man. The comprehensive physical and data resources of EMMA support basic biomedical and preclinical research, and the available research tools and mouse/rat models of human disease offer the opportunity to develop a better understanding of molecular disease mechanisms and may provide the foundation for the development of diagnostic, prognostic and therapeutic strategies. EMMA is a founding member of the Federation of International Mouse Resources (FIMRe).
The Scientific User Support Team may be addressed
EMMA is supported by the partner institutions, national research programs and by the EC’s Research and Innovation programme Horizon 2020 (H2020-EU.22.214.171.124. Developing new world class research infrastructures).
EMMA’s primary objective is to establish and manage a unified repository for maintaining medically relevant mouse and rat mutants and making them available to the scientific community. Therefore, EMMA archives mutant strains and distributes them to requesting researchers. EMMA also hosts courses in cryopreservation to promote the use and dissemination of frozen embryos and spermatozoa. Dissemination of knowledge is further fostered by a dedicated resource database.
The EMMA network is a partnership of several laboratories and other institutions throughout Europe. The current membership includes:
Biomedical Research Center `Alexander Fleming´, Vari, Greece
PHENOMIN-ICS Institut Clinique de la Souris, Illkirch, France
Consiglio Nazionale delle Ricerche (CNR), Monterotondo, Italy
PHENOMIN-TAAM, Orléans, France
National Centre for Biotechnology (CNB-CSIC), Madrid, Spain
European Bioinformatics Institute (EMBL-EBI), Hinxton, United Kingdom
Helmholtz Munich (HM), Neuherberg, Germany
INFRAFRONTIER GmbH, Munich, Germany
Instituto Gulbenkian de Ciência, Oeiras, Portugal
The Centre for Phenogenomics (TCP), Prague, Czech Republic
Karolinska Institutet, Stockholm, Sweden
MRC Harwell Institute, Harwell, United Kingdom
The Netherlands Cancer Institute, Amsterdam, The Netherlands
Tel Aviv University (TAU), Tel Aviv, Israel
University of Oulu, Oulu, Finland
University of Veterinary Medicine Vienna, Vienna, Austria
EMMA is open for the incorporation of new members into the current network and detailed guidelines for this process are established.
The EMMA network is directed by Professor Martin Hrabé de Angelis who heads the Institute of Experimental Genetics and of the German Mouse Clinic (GMC) at the Helmholtz Zentrum München.