B6;129S5-Arhgef18Gt(OSTGST002860)Lex/Ieg

Status

Available to order

EMMA IDEM:02310
International strain nameB6;129S5-Arhgef18Gt(OSTGST002860)Lex/Ieg
Alternative nameLEXKO-650, REC2_2
Strain typeGene-trap
Allele/Transgene symbolArhgef18Gt(OSTGST002860)Lex
Gene/Transgene symbolArhgef18

Information from provider

Provider Lexicon Genetics, Inc.
Provider affiliationLexicon Pharmaceuticals
Phenotypic informationGenetic data indicate that the mutation resulted in reduced viability of the homozygous mutants. No notable phenotype was observed for the heterozygous mice. Due to greatly reduced viability, transcript expression analysis was not performed.
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal retina morphology / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • increased circulating amylase level / IMPC
  • preweaning lethality, complete penetrance / IMPC
MGI phenotypes (allele matching)
  • preweaning lethality, incomplete penetrance / MGI
MGI phenotypes (gene matching)
  • no phenotypic analysis / MGI
  • preweaning lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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