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Get an overview of INFRAFRONTIER and everything around us.
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INFRAFRONTIER collaborates widely on the European and international level to enhance biomedical research.
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The welfare and ethical treatment of animal models in research is very important for INFRAFRONTIER.
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EMMA
EMMA Overview
Everything you need to know about the European Mouse Mutant Archive – EMMA.
Cryopreservation
EMMA archives your mouse/rat mutant free of charge.
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EMMA repository conditions, MTAs, policy on licensing and use restriction.
Strain Distribution
Access to over 8800 mouse mutants and a couple of tens of rat mutants.
Strain Collections
Strains originated by large-scale projects archived and distributed by EMMA.
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Validated protocols and training videos.
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Find the mutant strain you need for your research!
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Services Overview
INFRAFRONTIER offers a host of state-of-the-art services to the biomedical community with the aim to understand and combat human diseases.
Rodent Model Generation
Generation of rodent models using latest genome-editing technologies.
Strain Distribution
Distribution of mutant mouse/rat lines around the globe as frozen gametes or live cohorts.
Cryopreservation
Archiving of mutant mouse/rat models generated by researchers around the world.
Systemic Phenotyping
Mouse model phenotyping platforms incorporating whole-system screens.
Axenic Service
Germ-free derivation of mouse strains for gnotobiotic studies.
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Specialised INFRAFRONTIER resources and services for specific disease areas.
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Popular Search Terms:
CD11
Rosa26
Cre
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EUCOMM
Immune
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Search results for "Acad12" in category
Genes/Alleles
(2 EMMA strains found)
EMMA ID
Strain name
Gene symbol
Disease count
EM:14268
C57BL/6N-Acad12
tm1b(EUCOMM)Wtsi
/WtsiPh
Acad12
Register interest
EM:07179
C57BL/6N-A
tm1Brd
Acad12
tm1a(EUCOMM)Wtsi
/WtsiCnrm
Acad12
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Cardiovascular system
Heart disease
Atrioventricular spetal defect
Dilated cardiomyopathy
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Jervell-Lange Nielsen syndrome
Tetralogy of Fallot
Endocrine system
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Primary hyperaldosteronism
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Immune system
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Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome
Lymphatic system disease
Familial hemophagocytic lymphohistiocytosis 2
Hereditary lymphedema
Primary immunodeficiency disease
DNA ligase IV deficiency
T-cell immunodeficiency, congenital alopecia, and nail dystrophy
Hematopoietic system
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systemic scleroderma
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Osteogenesis imperfecta type
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Spondyloepiphyseal dysplasia congenita
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Nervous system
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Autosomal recessive early-onset Parkinson disease 7
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Peripheral nervous system disease
Charcot-Marie-Tooth disease type 1A
Charcot-Marie-Tooth disease type 2A2
Charcot-Marie-Tooth disease type 2D
Charcot-Marie-Tooth disease X-linked dominant 1
Brain disease
Basal ganglia calcification
Creutzfeldt-Jakob disease
Early infantile epileptic encephalopathy
Sensory system disease
Aniridia
Autosomal dominant nonsyndromic deafness 12
Autosomal dominant nonsyndromic deafness 36
Autosomal recessive nonsyndromic deafness 1A
Autosomal recessive nonsyndromic deafness 4A
Autosomal recessive nonsyndromic deafness 31
Autosomal recessive nonsyndromic deafness 7
Autosomal recessive nonsyndromic deafness 42
Cataract
Cataract 1 multiple types
Cataract 19 multiple types
Cataract 20 multiple types
Cataract 21 multiple types
Congenital stationary night blindness
Otitis media
Ocular albinism
Retinitis pigmentosa 40
Persistent hyperplastic primary vitreous
Respiratory system
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Urinary system
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Breast cancer
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Benign neoplasm
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Mental health
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Metabolism
Acquired metabolic disease
Familial hypocalciuric hypercalcemia 1
Metabolic syndrome X
Obesity
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Inherited metabolic disorder
Alkaptonuria
Aspartylglucosaminuria
Cutaneous porphyria
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Neuronal ceroid lipofuscinosis 3
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Neuronal ceroid lipofuscinosis 10
Favism
Genetic disease
Ciliopathy
Joubert syndrome 6
Meckel syndrome
Primary ciliary dyskinesia 7
Maturity-onset diabetes of the young
Maturity-onset diabetes of the young
Maturity-onset diabetes of the young type 2
Chondrodysplasia punctata
X-linked chondrodysplasia punctata
Monogenic disease
Branchiootorenal syndrome
Clouston syndrome<
Denys-Drash syndrome
Microphthalmia with limb anomalies
Nephronophthisis 2
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Waardenburg syndrome type 1
Waardenburg syndrome type 2A
Xeroderma pigmentosum variant type
Syndrome
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Selected strain collections
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TET-expression systems
Genome Editing Mice for Medicine – GEMM
Wellcome Trust Knockout Mouse Resource
PHENOMIN-ICS NR Collection
PHENOMIN-ICS Recombinase collection
Mosaic Analysis with Double Markers (MADM)
Rat strains
Curated Disease Models
