B6;129P2-Prmt2tm1Yah Cstbtm1Yah/+ +/Orl
Status | Available to order |
EMMA ID | EM:01810 |
International strain name | B6;129P2-Prmt2tm1Yah Cstbtm1Yah/+ +/Orl |
Alternative name | Cis (Hrmt1l1tm1Yah-Cstbtm1Yah) |
Strain type | Targeted Mutant Strains : Other targeted |
Allele/Transgene symbol | Cstbtm1Yah, |
Gene/Transgene symbol | Cstb |
Information from provider
Provider | Yann HERAULT |
Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
Genetic information | Insertion by homologous recombination in ES cells using MICER of a targeting vector containing a loxP site at the Hrmt1l1 (Prmt2) locus and of a second vector, on the same homologous chromosome, containing a loxP site at the Cstb locus (cis configuration of the loxP sites on MMU10). |
Phenotypic information | No visible phenotype. |
Breeding history | Targeted mutation generated in 129P2 ES cells. Cells injected in C57BL/6 blastocysts. Backcrossed to C57BL/6, then intercrossed. |
References |
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Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Unverricht-Lundborg disease / Orphanet_308
- Autosomal recessive hypohidrotic ectodermal dysplasia / Orphanet_248
MGI phenotypes (allele matching)
Literature references
- Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.;Duchon Arnaud, Besson Vanessa, Pereira Patricia Lopes, Magnol Laetitia, Hérault Yann, ;2008;Genetics;180;51-9; 18757940
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