C57BL/6N-Lap7tm1.1Ics/Ics
Status | Available to order |
EMMA ID | EM:15620 |
International strain name | C57BL/6N-Lap7tm1.1Ics/Ics |
Alternative name | Lap7tm1.1Ics (G4624) |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Larp7tm1.1Ics, |
Gene/Transgene symbol | Larp7 |
Information from provider
Provider | ICS, Institut Clinique de la Souris |
Provider affiliation | ICS, Institut Clinique de la Souris |
Genetic information | This line was obtained by modification of BD10 in house derived C57BL/6N embryonic stem cells. Exons 2 to 8 (ENSMUSE00000174832 to ENSMUSE00000353775) were floxed. The floxed fragment also contains the Mir302 miRNAs. The flipped NeoR cassette was removed by breeding the male chimeras with Flp recombinase deleter females. The line was generated on a pure C57BL/6N inbred genetic background. For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:Heterozygous:DOI: 10.3390/biomedicines10123148 |
Breeding history | Inbred C57BL/6N |
References |
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Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Literature references
- Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.;Meziane Hamid, Birling Marie-Christine, Wendling Olivia, Leblanc Sophie, Dubos Aline, Selloum Mohammed, Pavlovic Guillaume, Sorg Tania, Kalscheuer Vera M, Billuart Pierre, Laumonnier Frédéric, Chelly Jamel, van Bokhoven Hans, Herault Yann, ;2022;Biomedicines;10;; 36551904
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