- lymphoid neoplasms / IMPC
- hyperplasia / IMPC
- increased blood urea nitrogen level / IMPC
- decreased circulating HDL cholesterol level / IMPC
- decreased leukocyte cell number / IMPC
- decreased circulating LDL cholesterol level / IMPC
- increased circulating fructosamine level / IMPC
- decreased circulating cholesterol level / IMPC
- increased circulating creatinine level / IMPC
- decreased total body fat amount / IMPC
- increased bone mineral density / IMPC
- neoplasm / IMPC
C57BL/6N-Setd1atm1.2(IMPC)Wtsi/WtsiIeg
Status | Available to order |
EMMA ID | EM:14215 |
International strain name | C57BL/6N-Setd1atm1.2(IMPC)Wtsi/WtsiIeg |
Alternative name | BEPD0114_C12 |
Strain type | |
Allele/Transgene symbol | Setd1atm1.2(IMPC)Wtsi |
Gene/Transgene symbol | Setd1a |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from undef ES clone BEPD0114_C12. For further details on the construction of this clone see the page at the IMPC portal. ES cells were generated using the CRISPR/Cas9 technology. The details of the applied experimental procedures involving CRISPR/Cas9 technology are not available. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- increased bone mineral density / MGI
- decreased circulating LDL cholesterol level / MGI
- decreased circulating HDL cholesterol level / MGI
- decreased leukocyte cell number / MGI
- failure to gastrulate / MGI
- decreased circulating alanine transaminase level / MGI
- decreased circulating alkaline phosphatase level / MGI
- decreased rib number / MGI
- decreased circulating cholesterol level / MGI
- cellular phenotype / MGI
- abnormal cell physiology / MGI
- abnormal DNA methylation / MGI
- decreased total body fat amount / MGI
- embryonic lethality between implantation and somite formation, complete penetrance / MGI
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