IMPC phenotypes (gene matching)
B6J.129S2-Nr2c2tm1.2Ics/Ics
| Status | Available to order |
| EMMA ID | EM:12959 |
| International strain name | B6J.129S2-Nr2c2tm1.2Ics/Ics |
| Alternative name | TR4 KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Nr2c2tm1.2Ics |
| Gene/Transgene symbol | Nr2c2 |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:not knownHeterozygous:not known |
| Breeding history | 6 backcross generations |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased circulating LDL cholesterol level / MGI
- seminiferous tubule degeneration / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal eating behavior / MGI
- abnormal hemoglobin / MGI
- decreased inflammatory response / MGI
- reduced male fertility / MGI
- abnormal glucose homeostasis / MGI
- abnormal lipid homeostasis / MGI
- decreased susceptibility to hepatic steatosis / MGI
- decreased circulating triglyceride level / MGI
- oligozoospermia / MGI
- decreased circulating insulin level / MGI
- decreased circulating alanine transaminase level / MGI
- abnormal gas homeostasis / MGI
- decreased testis weight / MGI
- increased energy expenditure / MGI
- decreased circulating cholesterol level / MGI
- increased oxygen consumption / MGI
- abnormal energy homeostasis / MGI
- decreased circulating glucose level / MGI
- decreased circulating aspartate transaminase level / MGI
- decreased susceptibility to diet-induced obesity / MGI
- abnormal white adipose tissue physiology / MGI
- arrest of male meiosis / MGI
- increased carbon dioxide production / MGI
- decreased white fat cell size / MGI
- decreased abdominal fat pad weight / MGI
- decreased epididymal fat pad weight / MGI
- decreased liver triglyceride level / MGI
- abnormal blood homeostasis / MGI
- increased respiratory quotient / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- decreased body fat mass / MGI
- decreased brown adipose tissue mass / MGI
- multinucleated giant male germ cells / MGI