C57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph

Status

Available to order

EMMA IDEM:09379
International strain nameC57BL/6N-Gltptm1a(EUCOMM)Hmgu/Ph
Alternative nameB6.Gltptm1a
Strain typeTargeted Mutant Strains
Allele/Transgene symbolGltptm1a(EUCOMM)Hmgu
Gene/Transgene symbolGltp

Information from provider

ProviderDagmar Wachten
Provider affiliationMolecular Physiology, caesar - center of advanced european studies and research of the Max Planck Society
Genetic informationGltp gene was conditionally targeted by insertion of a reporter-tagged cassette containing lacZ, neomycin resistance, Frt and LoxP sequences. Exon 2 was targeted by homologous recombination and electroporation of the targeting construct into C57BL/6N ES cells. The targeting resulted in a so called "knockout-first allele". LacZ and neomycin cassettes together are flanked by Frt sites; neomycin cassette and targeted exon2 are flanked by LoxP sites.
Phenotypic informationHomozygous:
Not known, until now mice were bred on heterozygous basis only.

Heterozygous:
Heterozygous mice show no obvious phenotype and appear normal.
Breeding historyChimeric founder mice were generated by injection of C57BL/6N ES cells into C57BL/6J albino (B6(Cg)-Tyrc-2J/J) embryos. Chimeras were bred to C57BL/6N partner to test for germ-line transmission.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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Practical information

Example health report
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Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

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