Available to order

International strain nameB6;129P2-Mc2rtm1Dgen/H
Alternative nameDELTAGEN_T605
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolMc2rtm1Dgen,
Gene/Transgene symbolMc2r

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationHistopathology: Adrenal gland, hypoplasia (cortex and medulla); Brown adipose tissue, decreased cytoplasmic lipid vacuolation. Densitometry : Low fat % in homozygous mutant females. Behavior: Decreased metrazol response threshold; Increased total distance traveled in open field test; Decreased time immobile on tail suspension test. Changes related to genotype at 300 days: Histopathology : Adrenal gland, hypoplasia (cortex); Brown adipose tissue, decreased cytoplasmic lipid vacuolation. Densitometry : Low fat % in homozygous mutant females.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingheterozygous C57BL/6J
Stage of embryos2-cell

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • adrenal gland hypoplasia / MGI
  • increased anxiety-related response / MGI
  • hyperactivity / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • decreased percent body fat/body weight / MGI
  • adrenal cortical hyperplasia / MGI
  • decreased brown fat lipid droplet number / MGI

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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