C57BL/6J-Tbl1xr1em1H/H
| Status | Available to order |
| EMMA ID | EM:15688 |
| International strain name | C57BL/6J-Tbl1xr1em1H/H |
| Alternative name | C57BL/6J-Tbl1xr1 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Tbl1xr1em1H |
| Gene/Transgene symbol |
Information from provider
| Provider | Anita Boelen |
| Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
| Genetic information | CRISPR generated. The aim of the project was to introduce the Y446C change by altering one nucleotide. A silent mutation was also incorporated into the design to prevent re-processing of the allele by CRISPR Cas9. The founder used to generate this line was genotyped as having the legitimately repaired Y446C allele, an illegitimately repaired allele (Silent mutation only) and a 7 nt deletion. |
| Phenotypic information | Homozygous:No abnormal phenotype reportedHeterozygous:No abnormal phenotype reported |
| Breeding history | Incepient congenic on maintained background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |