Available to order

International strain nameNOD.B6-(D17Mit113-D17Mit260)/GhjOrl
Alternative nameNOD.B6-C17(R156)
Strain typeSpontaneous
Allele/Transgene symbolIdd23C57BL/6J,
Gene/Transgene symbolIdd23

Information from provider

ProviderHenri-Jean Garchon
Provider affiliationER70 CNRS et Unite 125 Inserm
Genetic informationNOD subcongenic strain with an interval proximal to the H2 complex from C57BL/6. The R156 interval is derived from R114.
Phenotypic informationThis line and the related lines, consomic, congenic and subcongenic for chromosome 17 and fragments of this chromosome, were derived to thoroughly investigate the role of the major histocompatibility complex (MHC) and MHC-linked genes in autoimmune predisposition, notably including type I diabetes (Idd1 and Idd16) loci and chronic autoimmune thyroiditis (Ceat1) locus, on the non-obese diabetic (NOD) background. The R156 line is partially protected against type 1 diabetes and defines the Idd16.2 locus for type 1 diabetes.
Breeding history20 generations of backcrosses followed by sister-brother matings. Selection of subcongenics by additional backcrosses.
ReferencesNone available

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal glucose homeostasis / MGI

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Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

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Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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