IMPC phenotypes (gene matching)
C57BL/6N-Atm1Brd Ackr3tm2a(EUCOMM)Wtsi/IcsOrl
| Status | Available to order |
| EMMA ID | EM:09984 |
| Citation information | RRID:IMSR_EM:09984 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Atm1Brd Ackr3tm2a(EUCOMM)Wtsi/IcsOrl |
| Alternative name | EPD0830_1_D06 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Ackr3tm2a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Ackr3 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0830_1_D06. For further details on the construction of this clone see the page at the IKMC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6NTac males |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal heart morphology / MGI
- overriding aortic valve / MGI
- enlarged heart / MGI
- heart hyperplasia / MGI
- abnormal interventricular septum morphology / MGI
- abnormal atrioventricular cushion morphology / MGI
- abnormal cardiovascular system physiology / MGI
- cyanosis / MGI
- abnormal blood vessel morphology / MGI
- abnormal atrial thrombosis / MGI
- lung inflammation / MGI
- hemorrhage / MGI
- respiratory distress / MGI
- premature death / MGI
- abnormal semilunar valve morphology / MGI
- abnormal aortic valve morphology / MGI
- abnormal pulmonary valve morphology / MGI
- dilated heart right ventricle / MGI
- dilated heart atrium / MGI
- cardiac fibrosis / MGI
- nervous system phenotype / MGI
- myocardial fiber degeneration / MGI
- digestive/alimentary phenotype / MGI
- immune system phenotype / MGI
- hematopoietic system phenotype / MGI
- pulmonary fibrosis / MGI
- calcified aortic valve / MGI
- aortic valve stenosis / MGI
- abnormal cardiac outflow tract development / MGI
- pulmonary valve stenosis / MGI
- decreased marginal zone B cell number / MGI
- decreased survivor rate / MGI
- ventricular septal defect / MGI
- atrial septal defect / MGI
- perimembraneous ventricular septal defect / MGI
- abnormal heart and great artery attachment / MGI
- thick aortic valve / MGI
- thick pulmonary valve / MGI
- postnatal lethality, incomplete penetrance / MGI
- neonatal lethality, complete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- perinatal lethality, complete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI