C57BL/6NTac-Tmem108tm1a(EUCOMM)Wtsi/IcsOrl
Status | Available to order |
EMMA ID | EM:09972 |
International strain name | C57BL/6NTac-Tmem108tm1a(EUCOMM)Wtsi/IcsOrl |
Alternative name | EPD0511_5_D01 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Tmem108tm1a(EUCOMM)Wtsi |
Gene/Transgene symbol | Tmem108 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | ICS, Institut Clinique de la Souris |
Provider affiliation | ICS, Institut Clinique de la Souris |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0511_5_D01. For further details on the construction of this clone see the page at the IKMC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous C57BL/6NTac |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal CNS synaptic transmission / MGI
- reduced sensorimotor gating / MGI
- abnormal excitatory postsynaptic currents / MGI
- abnormal miniature excitatory postsynaptic currents / MGI
- abnormal spatial working memory / MGI
- decreased prepulse inhibition / MGI
- impaired contextual conditioning behavior / MGI
- abnormal dendritic spine morphology / MGI
- abnormal hippocampus granule cell morphology / MGI
- decreased excitatory postsynaptic current amplitude / MGI
- abnormal dentate gyrus neuron dendrite morphology / MGI
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