IMPC phenotypes (gene matching)
- short tibia / IMPC
STOCK Mmp9tm1a(EUCOMM)Wtsi/IcsOrl
| Status | Available to order |
| EMMA ID | EM:09960 |
| International strain name | STOCK Mmp9tm1a(EUCOMM)Wtsi/IcsOrl |
| Alternative name | EPD0844_5_F12 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Mmp9tm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Mmp9 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0844_5_F12. For further details on the construction of this clone see the page at the IKMC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6NTac |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Metaphyseal anadysplasia / Orphanet_1040
MGI phenotypes (gene matching)
- delayed bone ossification / MGI
- osteopetrosis / MGI
- abnormal trabecular bone morphology / MGI
- abnormal long bone hypertrophic chondrocyte zone / MGI
- increased monocyte cell number / MGI
- abnormal megakaryocyte differentiation / MGI
- abnormal angiogenesis / MGI
- altered response to myocardial infarction / MGI
- abnormal myelination / MGI
- increased body weight / MGI
- decreased metastatic potential / MGI
- reduced long term potentiation / MGI
- impaired myelopoiesis / MGI
- impaired hematopoiesis / MGI
- myocarditis / MGI
- lung inflammation / MGI
- decreased inflammatory response / MGI
- reduced fertility / MGI
- decreased litter size / MGI
- decreased tumor incidence / MGI
- abnormal dendritic cell physiology / MGI
- decreased susceptibility to viral infection / MGI
- decreased susceptibility to bacterial infection / MGI
- increased susceptibility to viral infection / MGI
- abnormal neutrophil physiology / MGI
- decreased IgE level / MGI
- increased IgE level / MGI
- short tibia / MGI
- increased susceptibility to dystrophic cardiac calcinosis / MGI
- delayed wound healing / MGI
- joint inflammation / MGI
- joint swelling / MGI
- thick ventricular wall / MGI
- abnormal cytokine secretion / MGI
- decreased myocardial infarction size / MGI
- hypoalgesia / MGI
- abnormal long bone epiphyseal plate morphology / MGI
- increased vascular permeability / MGI
- abnormal metatarsal bone morphology / MGI
- short femur / MGI
- abnormal impulse conducting system conduction / MGI
- cardiac fibrosis / MGI
- decreased neuron apoptosis / MGI
- increased width of hypertrophic chondrocyte zone / MGI
- decreased susceptibility to induced arthritis / MGI
- abnormal tumor morphology / MGI
- abnormal intestinal goblet cell morphology / MGI
- abnormal response/metabolism to endogenous compounds / MGI
- abnormal physiological neovascularization / MGI
- abnormal myocardial fiber physiology / MGI
- decreased length of long bones / MGI
- decreased susceptibility to experimental autoimmune encephalomyelitis / MGI
- abnormal hematopoietic stem cell morphology / MGI
- abnormal vascular wound healing / MGI
- increased eosinophil cell number / MGI
- increased lymphocyte cell number / MGI
- abnormal response to infection / MGI
- decreased cardiac muscle contractility / MGI
- decreased susceptibility to injury / MGI
- abnormal blood-brain barrier function / MGI
- increased T cell proliferation / MGI
- abnormal Langerhans cell physiology / MGI
- immune system phenotype / MGI
- increased macrophage cell number / MGI
- abnormal vascular smooth muscle physiology / MGI
- increased ventricle muscle contractility / MGI
- increased angiogenesis / MGI
- increased susceptibility to type IV hypersensitivity reaction / MGI
- decreased susceptibility to ischemic brain injury / MGI
- abnormal retinal apoptosis / MGI
- aortic aneurysm / MGI
- increased T-helper 2 cell number / MGI
- decreased dendritic cell number / MGI
- abnormal leukocyte morphology / MGI
- decreased susceptibility to induced colitis / MGI
- increased interferon-gamma secretion / MGI
- decreased interferon-gamma secretion / MGI
- increased circulating interferon-beta level / MGI
- increased circulating interferon-gamma level / MGI
- decreased circulating interleukin-10 level / MGI
- increased interleukin-13 secretion / MGI
- increased interleukin-4 secretion / MGI
- increased interleukin-5 secretion / MGI
- abnormal chemokine level / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- abnormal bone marrow cell physiology / MGI
- increased tibialis anterior weight / MGI
- impaired contextual conditioning behavior / MGI
- abnormal induced retinal neovascularization / MGI
- increased sensitivity to xenobiotic induced morbidity/mortality / MGI
- decreased sensitivity to xenobiotic induced morbidity/mortality / MGI
- decreased susceptibility to viral infection induced morbidity/mortality / MGI
- increased susceptibility to viral infection induced morbidity/mortality / MGI
- decreased oligodendrocyte number / MGI
- increased prostaglandin level / MGI
- thick interventricular septum / MGI
- decreased histamine level / MGI