MGI phenotypes (gene matching)
C3H.C-Phf11dm1H/H
| Status | Available to order |
| EMMA ID | EM:09935 |
| Citation information | RRID:IMSR_EM:09935 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3H.C-Phf11dm1H/H |
| Alternative name | Phf11d V103A |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Phf11dm1H |
| Gene/Transgene symbol | Phf11d |
Information from provider
| Provider | Janet Kenyon |
| Provider affiliation | MRC Harwell |
| Genetic information | ENU point mutation affected Phf11d (valine 103 substitution for alanine). |
| Phenotypic information | Homozygous:None. On exposure to LPS mice have altered immune response in lungs compared to that seen in control mice (an asthma related phenotype.)Heterozygous:None |
| Breeding history | Mutation was induced on BALB/c, subsequently back crossed 10 generations onto C3H/HeH |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.;Zhang Youming, Dean Charlotte, Chessum Lauren, Nguyen Dao, Stewart Michelle, Taylor Martin, Cookson William O, Moffatt Miriam F, ;2014;Mammalian genome : official journal of the International Mammalian Genome Society;25;573-82; 25091723