C57BL/6J-Tg(tetO-ARAP1,-luc)1Rttr/H
| Status | Available to order |
| EMMA ID | EM:09785 |
| Citation information | RRID:IMSR_EM:09785 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Tg(tetO-ARAP1,-luc)1Rttr/H |
| Alternative name | Arap1-tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(tetO-ARAP1,-luc)1Rttr |
| Gene/Transgene symbol | Tg(tetO-ARAP1,-luc)1Rttr |
Information from provider
| Provider | Guy Rutter |
| Provider affiliation | Section of Cell Biology, Department of Medicine, Imperial College London |
| Genetic information | Insertion of a coding cassette under the control of a bidirectional tetracycline-regulated promoter driving the expression of both human flag-ARAP1 and firefly luciferase. Vector used for the subcloning of the transgene incorporated on this strain: pBI-L Vector PT3069-5 GenBank Accession No.:U89934 Catalog No. 631005. |
| Phenotypic information | Homozygous:N/AHeterozygous:Overexpression of the transgene after crossing with mice expressing the reverse tetracycline transactivator and given doxycycline in drinking water (possibility of inducing overexpression in a specific tissue). |
| Breeding history | Founder crossed with wild-type C57BL/6J to obtain F1; F1 crossed with wild-type C57BL/6J to obtain F2 to ensure the stability of the line (only one insertion site in the genome). |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |