FVB-Tg(CD19-Zap70)1Icgb/Cnrm
| Status | Available to order |
| EMMA ID | EM:09109 |
| Citation information | RRID:IMSR_EM:09109 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Tg(CD19-Zap70)1Icgb/Cnrm |
| Alternative name | FVB-Tg(CD19-Zap70)1Icgb |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CD19-Zap70)1Icgb |
| Gene/Transgene symbol | Tg(CD19-Zap70)1Icgb |
Information from provider
| Provider | Stefania Gobessi |
| Provider affiliation | ICGEB |
| Genetic information | Transgenic expression of Zap70 in B lymphocytes |
| Phenotypic information | Homozygous:Not investigated.Heterozygous:None identified so far. These mice were generated to investigate the effects of Zap70 overexpression on chronic lymphocytic leukemia development and behaviour using the Em-TCL1 transgenic mouse model of the disease. This strain delays leukemia development when crossed with Em-TCL1 transgenic mice. |
| Breeding history | 7 incrosses |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |