IMPC phenotypes (gene matching)
C57BL/6N-Pdpntm1c(EUCOMM)Wtsi/H
| Status | Available to order |
| EMMA ID | EM:09046 |
| International strain name | C57BL/6N-Pdpntm1c(EUCOMM)Wtsi/H |
| Alternative name | EPD0636_3_A10 |
| Strain type | Targeted Mutant Strains : Targeted Conditional |
| Allele/Transgene symbol | Pdpntm1c(EUCOMM)Wtsi |
| Gene/Transgene symbol | Pdpn |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This line originates from EUCOMM ES clone EPD0636_3_A10, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal heart development / MGI
- abnormal interventricular septum morphology / MGI
- decreased atrioventricular cushion size / MGI
- abnormal lung morphology / MGI
- atelectasis / MGI
- thick pulmonary interalveolar septum / MGI
- cyanosis / MGI
- abnormal lymphatic vessel morphology / MGI
- respiratory failure / MGI
- abnormal myocardial trabeculae morphology / MGI
- abnormal pulmonary alveolus morphology / MGI
- abnormal type I pneumocyte morphology / MGI
- thin myocardium / MGI
- abnormal epicardium morphology / MGI
- intestinal edema / MGI
- lymphedema / MGI
- abnormal lymph circulation / MGI
- lymphangiectasis / MGI
- abnormal myocardium compact layer morphology / MGI
- abnormal coronary artery morphology / MGI
- abnormal fetal growth/weight/body size / MGI
- lethargy / MGI
- abnormal myocardium layer morphology / MGI
- homeostasis/metabolism phenotype / MGI
- skeleton phenotype / MGI
- increased fetal weight / MGI
- abnormal skin appearance / MGI
- abnormal heart and great artery attachment / MGI
- neonatal lethality, complete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI