IMPC phenotypes (allele matching)
C57BL/6N-Atm1Brd Pth1rtm1a(EUCOMM)Hmgu/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:08867 |
| Citation information | RRID:IMSR_EM:08867 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Atm1Brd Pth1rtm1a(EUCOMM)Hmgu/WtsiIeg |
| Alternative name | HEPD0733_7_D02 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Pth1rtm1a(EUCOMM)Hmgu |
| Gene/Transgene symbol | Pth1r |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
|
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0733_7_D02. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Ollier disease / Orphanet_296
- Primary failure of tooth eruption / Orphanet_412206
- Metaphyseal chondrodysplasia, Jansen type / Orphanet_33067
- Blomstrand lethal chondrodysplasia / Orphanet_50945
- Eiken syndrome / Orphanet_79106
MGI phenotypes (allele matching)
- abnormal thymus morphology / MGI
- abnormal lens morphology / MGI
- hemorrhage / MGI
- abnormal brain morphology / MGI
- increased hemangioma incidence / MGI
- dilated bile duct / MGI
- enlarged lymphatic vessel / MGI
- abnormal inferior vena cava valve morphology / MGI
- herniated liver / MGI
- decreased total retina thickness / MGI
- absent segment of posterior cerebral artery / MGI
- retropharyngeal edema / MGI
- enlarged paraumbilical vein / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve morphology / MGI
- jugular vein stenosis / MGI
- blood in lymph vessels / MGI
- anastomosis between internal carotid artery and basilar artery / MGI
- abnormal vertebral artery topology / MGI
MGI phenotypes (gene matching)
- abnormal neurocranium morphology / MGI
- short mandible / MGI
- abnormal long bone hypertrophic chondrocyte zone / MGI
- increased circulating calcium level / MGI
- domed cranium / MGI
- short snout / MGI
- short limbs / MGI
- abnormal thymus morphology / MGI
- atelectasis / MGI
- abnormal lens morphology / MGI
- abnormal circulating phosphate level / MGI
- decreased embryo size / MGI
- postnatal growth retardation / MGI
- hemorrhage / MGI
- respiratory failure / MGI
- abnormal limb morphology / MGI
- abnormal skeleton development / MGI
- abnormal brain morphology / MGI
- abnormal bone mineralization / MGI
- decreased circulating parathyroid hormone level / MGI
- increased hemangioma incidence / MGI
- abnormal long bone epiphyseal plate morphology / MGI
- dilated bile duct / MGI
- small lung / MGI
- abnormal long bone epiphyseal plate proliferative zone / MGI
- embryonic growth retardation / MGI
- abnormal synchondrosis / MGI
- decreased fetal size / MGI
- long tibia / MGI
- decreased length of long bones / MGI
- abnormal osteoblast physiology / MGI
- respiratory system phenotype / MGI
- abnormal hyaline cartilage morphology / MGI
- abnormal blood homeostasis / MGI
- protruding tongue / MGI
- enlarged lymphatic vessel / MGI
- abnormal inferior vena cava valve morphology / MGI
- herniated liver / MGI
- neonatal lethality, complete penetrance / MGI
- perinatal lethality, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- decreased total retina thickness / MGI
- absent segment of posterior cerebral artery / MGI
- retropharyngeal edema / MGI
- enlarged paraumbilical vein / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve morphology / MGI
- jugular vein stenosis / MGI
- blood in lymph vessels / MGI
- anastomosis between internal carotid artery and basilar artery / MGI
- abnormal vertebral artery topology / MGI
- premature chondrocyte differentiation / MGI
- foramen magnum stenosis / MGI