IMPC phenotypes (allele matching)
C57BL/6N-Atm1Brd Pth1rtm1a(EUCOMM)Hmgu/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:08867 |
| International strain name | C57BL/6N-Atm1Brd Pth1rtm1a(EUCOMM)Hmgu/WtsiIeg |
| Alternative name | HEPD0733_7_D02 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Pth1rtm1a(EUCOMM)Hmgu |
| Gene/Transgene symbol | Pth1r |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0733_7_D02. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Ollier disease / Orphanet_296
- Primary failure of tooth eruption / Orphanet_412206
- Metaphyseal chondrodysplasia, Jansen type / Orphanet_33067
- Blomstrand lethal chondrodysplasia / Orphanet_50945
- Eiken syndrome / Orphanet_79106
MGI phenotypes (allele matching)
- abnormal thymus morphology / MGI
- abnormal lens morphology / MGI
- hemorrhage / MGI
- abnormal brain morphology / MGI
- increased hemangioma incidence / MGI
- dilated bile duct / MGI
- enlarged lymphatic vessel / MGI
- abnormal inferior vena cava valve morphology / MGI
- herniated liver / MGI
- decreased total retina thickness / MGI
- absent segment of posterior cerebral artery / MGI
- retropharyngeal edema / MGI
- enlarged paraumbilical vein / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve morphology / MGI
- jugular vein stenosis / MGI
- blood in lymph vessels / MGI
- anastomosis between internal carotid artery and basilar artery / MGI
- abnormal vertebral artery topology / MGI
MGI phenotypes (gene matching)
- abnormal neurocranium morphology / MGI
- short mandible / MGI
- abnormal long bone hypertrophic chondrocyte zone / MGI
- increased circulating calcium level / MGI
- domed cranium / MGI
- short snout / MGI
- short limbs / MGI
- abnormal thymus morphology / MGI
- atelectasis / MGI
- abnormal lens morphology / MGI
- abnormal circulating phosphate level / MGI
- decreased embryo size / MGI
- postnatal growth retardation / MGI
- hemorrhage / MGI
- respiratory failure / MGI
- abnormal limb morphology / MGI
- abnormal skeleton development / MGI
- abnormal brain morphology / MGI
- abnormal bone mineralization / MGI
- decreased circulating parathyroid hormone level / MGI
- increased hemangioma incidence / MGI
- abnormal long bone epiphyseal plate morphology / MGI
- dilated bile duct / MGI
- small lung / MGI
- abnormal long bone epiphyseal plate proliferative zone / MGI
- embryonic growth retardation / MGI
- abnormal synchondrosis / MGI
- decreased fetal size / MGI
- long tibia / MGI
- decreased length of long bones / MGI
- abnormal osteoblast physiology / MGI
- respiratory system phenotype / MGI
- abnormal hyaline cartilage morphology / MGI
- abnormal blood homeostasis / MGI
- protruding tongue / MGI
- enlarged lymphatic vessel / MGI
- abnormal inferior vena cava valve morphology / MGI
- herniated liver / MGI
- neonatal lethality, complete penetrance / MGI
- perinatal lethality, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- decreased total retina thickness / MGI
- absent segment of posterior cerebral artery / MGI
- retropharyngeal edema / MGI
- enlarged paraumbilical vein / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve morphology / MGI
- jugular vein stenosis / MGI
- blood in lymph vessels / MGI
- anastomosis between internal carotid artery and basilar artery / MGI
- abnormal vertebral artery topology / MGI
- premature chondrocyte differentiation / MGI
- foramen magnum stenosis / MGI