- abnormal lens morphology / IMPC
- irregularly shaped pupil / IMPC
- abnormal retina morphology / IMPC
- increased startle reflex / IMPC
- abnormal retina vasculature morphology / IMPC
- increased circulating alkaline phosphatase level / IMPC
- increased circulating aspartate transaminase level / IMPC
- increased blood urea nitrogen level / IMPC
- abnormal retina blood vessel morphology / IMPC
- decreased total retina thickness / IMPC
C57BL/6N-Pkigtm1b(EUCOMM)Hmgu/Ieg
Status | Available to order |
EMMA ID | EM:08420 |
International strain name | C57BL/6N-Pkigtm1b(EUCOMM)Hmgu/Ieg |
Alternative name | HEPD0738_3_C12 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Pkigtm1b(EUCOMM)Hmgu |
Gene/Transgene symbol | Pkig |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from EUCOMM ES clone HEPD0738_3_C12. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele. Click here for more information on EUCOMM final vectors. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6NTacUSA |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased blood urea nitrogen level / IMPC
- increased startle reflex / IMPC
- abnormal retina morphology / IMPC
- abnormal retina vasculature morphology / IMPC
- decreased total retina thickness / IMPC
- abnormal retina blood vessel morphology / IMPC
- irregularly shaped pupil / IMPC
- abnormal lens morphology / IMPC
- increased circulating aspartate transaminase level / IMPC
- increased circulating alkaline phosphatase level / IMPC
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