C57BL/6N-Dnertm3b(EUCOMM)Hmgu/Ieg
Status | Available to order |
EMMA ID | EM:08394 |
International strain name | C57BL/6N-Dnertm3b(EUCOMM)Hmgu/Ieg |
Alternative name | HEPD0546_6_A10 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Dnertm3b(EUCOMM)Hmgu |
Gene/Transgene symbol | Dner |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from EUCOMM ES clone HEPD0546_6_A10. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele. Click here for more information on EUCOMM final vectors. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6NTacUSA |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- abnormal cerebellum development / MGI
- abnormal cerebellar foliation / MGI
- abnormal cerebellum external granule cell layer morphology / MGI
- abnormal CNS glial cell morphology / MGI
- impaired coordination / MGI
- ectopic Bergmann glia cells / MGI
- abnormal excitatory postsynaptic currents / MGI
- abnormal Purkinje cell innervation / MGI
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