B6.129P2-Mirc21tm1Doca/Cnrm
Status | Available to order |
EMMA ID | EM:08372 |
International strain name | B6.129P2-Mirc21tm1Doca/Cnrm |
Alternative name | mir-34bc FLOX |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Mirc21tm1Doca |
Gene/Transgene symbol | Mirc21 |
Information from provider
Provider | Donal O'Carroll |
Provider affiliation | Mouse Biology Unit, EMBL |
Genetic information | Two loxP site surrounding the exons coding for the pri-Mir34b and pri-Mir34c in chromosome 9. |
Phenotypic information | Homozygous:No phenotypeHeterozygous:No phenotype |
Breeding history | Backcrossed to C57BL/6N, N=12 |
References |
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Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
Literature references
- Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci.;Comazzetto Stefano, Di Giacomo Monica, Rasmussen Kasper Dindler, Much Christian, Azzi Chiara, Perlas Emerald, Morgan Marcos, O'Carroll Dónal, ;2014;PLoS genetics;10;e1004597; 25329700
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