IMPC phenotypes (gene matching)
B6.Cg-Zbed6tm1.2Sson/Kctt
| Status | Available to order |
| EMMA ID | EM:08120 |
| International strain name | B6.Cg-Zbed6tm1.2Sson/Kctt |
| Alternative name | Zbed6-/- |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Zbed6tm1.2Sson |
| Gene/Transgene symbol | Zbed6 |
Information from provider
| Provider | Leif Andersson |
| Provider affiliation | Department of Medical Biochemistry and Microbiology, Uppsala University |
| Genetic information | Knock-out model for the Zbed6 gene. |
| Phenotypic information | Homozygous:Indication of higher weight in homozygous KO mice compared to heterozygotes and wild-type.Heterozygous:Indication of higher weight in heterozygous mice compared to wild-type. |
| Breeding history | Line was generated in C57BL/6 ES cells (Bruce4). |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals.;Younis Shady, Schönke Milena, Massart Julie, Hjortebjerg Rikke, Sundström Elisabeth, Gustafson Ulla, Björnholm Marie, Krook Anna, Frystyk Jan, Zierath Juleen R, Andersson Leif, ;2018;Proceedings of the National Academy of Sciences of the United States of America;115;E2048-E2057; 29440408