C57BL/6NTac-Xiaptm1a(EUCOMM)Hmgu/IcsOrl
Status | Available to order |
EMMA ID | EM:07718 |
Citation information | RRID:IMSR_EM:07718 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NTac-Xiaptm1a(EUCOMM)Hmgu/IcsOrl |
Alternative name | HEPD0523_5_A03 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Xiaptm1a(EUCOMM)Hmgu |
Gene/Transgene symbol | Xiap |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | ICS, Institut Clinique de la Souris |
Provider affiliation | ICS, Institut Clinique de la Souris |
Genetic information | This mouse line originates from EUCOMM ES clone HEPD0523_5_A03. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous C57BL/6NTac males |
Breeding at archiving centre | The mutation is on chromosome X |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- X-linked lymphoproliferative disease due to XIAP deficiency / Orphanet_538934
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- enlarged pericardium / MGI
- abnormal mammary gland development / MGI
- hemorrhage / MGI
- no abnormal phenotype detected / MGI
- abnormal heart atrium morphology / MGI
- abnormal milk composition / MGI
- decreased cardiac muscle contractility / MGI
- hemopericardium / MGI
- immune system phenotype / MGI
- reproductive system phenotype / MGI
- congestive heart failure / MGI
- increased sensitivity to induced cell death / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- hypolactation / MGI
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