IMPC phenotypes (allele matching)
C57BL/6NTac-Lhx1tm1e(EUCOMM)Wtsi/IcsOrl
| Status | Available to order |
| EMMA ID | EM:07692 |
| International strain name | C57BL/6NTac-Lhx1tm1e(EUCOMM)Wtsi/IcsOrl |
| Alternative name | EPD0243_4_E03 |
| Strain type | Targeted Mutant Strains : Targeted Non-conditional |
| Allele/Transgene symbol | Lhx1tm1e(EUCOMM)Wtsi |
| Gene/Transgene symbol | Lhx1 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
|
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0243_4_E03. For further details on the construction of this clone see the page at the IMPC portal. The targeted allele has lost the 3' loxP site. These mutations cannot be converted into conditional alleles. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6NTac, wild-type C57BL/6N Tac |
| Stage of embryos | 8-cell |
Disease and phenotype information
MGI phenotypes (gene matching)
- absent kidney / MGI
- abnormal brain development / MGI
- abnormal spinal cord morphology / MGI
- abnormal female reproductive system morphology / MGI
- abnormal male reproductive system morphology / MGI
- decreased embryo size / MGI
- incomplete embryo turning / MGI
- abnormal allantois morphology / MGI
- abnormal neural tube morphology / MGI
- no abnormal phenotype detected / MGI
- abnormal gastrulation movements / MGI
- abnormal primitive streak formation / MGI
- no phenotypic analysis / MGI
- abnormal egg cylinder morphology / MGI
- absent ovary / MGI
- absent ureter / MGI
- abnormal primitive node morphology / MGI
- dilated allantois / MGI
- small allantois / MGI
- abnormal rostral-caudal axis patterning / MGI
- agonadal / MGI
- abnormal hindbrain development / MGI
- absent testes / MGI
- acephaly / MGI
- perinatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- absent metanephros / MGI
- absent midbrain / MGI
- embryonic-extraembryonic boundary constriction / MGI
- absent forebrain / MGI
- rostral-caudal axis duplication / MGI
- absent prechordal mesoderm / MGI
- abnormal primitive streak elongation / MGI
- abnormal anterior head development / MGI