FVB-Tg(Pax6-cre,GFP)2Pgr/PgrCnrm
| Status | Under development - register interest |
| EMMA ID | EM:00756 |
| Citation information | RRID:IMSR_EM:00756 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Tg(Pax6-cre,GFP)2Pgr/PgrCnrm |
| Alternative name | ECG |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Pax6-cre,GFP)2Pgr |
| Gene/Transgene symbol | Tg(Pax6-cre,GFP)2Pgr |
Information from provider
| Provider | Ruth Ashery-Padan |
| Provider affiliation | Sackler Faculty of Medicine, Tel Aviv University, Israel |
| Genetic information | A 2.2 kb element of Pax6 (driving Pax6 expression in the neuroretina) and the first Pax6 promoter (P0) were cloned upstream of the cre recombinase, IRES and GFP reporter sequences. |
| Phenotypic information | none |
| Breeding history | Maintained by mating heterozygous transgenic animals to wild-type FVB mice (backcross) for 8 generations (N7) |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | heterozygous FVB/N males, wild-type FVB/N females |
| Stage of embryos | 2-cell |
Literature references
- Pax6 is required for the multipotent state of retinal progenitor cells.;Marquardt T, Ashery-Padan R, Andrejewski N, Scardigli R, Guillemot F, Gruss P, ;2001;Cell;105;43-55; 11301001