FVB-Tg(Pax6-cre,GFP)2Pgr/PgrCnrm

Status	Available to order
EMMA ID	EM:00756
International strain name	FVB-Tg(Pax6-cre,GFP)2Pgr/PgrCnrm
Alternative name	ECG
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Pax6-cre,GFP)2Pgr
Gene/Transgene symbol	Tg(Pax6-cre,GFP)2Pgr

Information from provider

Provider	Ruth Ashery-Padan
Provider affiliation	Sackler Faculty of Medicine, Tel Aviv University, Israel
Genetic information	A 2.2 kb element of Pax6 (driving Pax6 expression in the neuroretina) and the first Pax6 promoter (P0) were cloned upstream of the cre recombinase, IRES and GFP reporter sequences.
Phenotypic information	none
Breeding history	Maintained by mating heterozygous transgenic animals to wild-type FVB mice (backcross) for 8 generations (N7)
References	Pax6 is required for the multipotent state of retinal progenitor cells.;Marquardt T, Ashery-Padan R, Andrejewski N, Scardigli R, Guillemot F, Gruss P, ;2001;Cell;105;43-55; 11301001

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy
Animals used for archiving	heterozygous FVB/N, wild-type FVB/N
Stage of embryos	2-cell

Literature references

Pax6 is required for the multipotent state of retinal progenitor cells.;Marquardt T, Ashery-Padan R, Andrejewski N, Scardigli R, Guillemot F, Gruss P, ;2001;Cell;105;43-55; 11301001

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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