IMPC phenotypes (gene matching)
C57BL/6N-Marveld2tm1a(EUCOMM)Wtsi/H
| Status | Available to order |
| EMMA ID | EM:07498 |
| Citation information | RRID:IMSR_EM:07498 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Marveld2tm1a(EUCOMM)Wtsi/H |
| Alternative name | EPD0597_2_G11 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Marveld2tm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Marveld2 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0597_2_G11. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive non-syndromic sensorineural deafness type DFNB / Orphanet_90636
MGI phenotypes (gene matching)
- abnormal organ of Corti morphology / MGI
- abnormal stria vascularis morphology / MGI
- abnormal myocardial fiber morphology / MGI
- increased body weight / MGI
- deafness / MGI
- increased heart weight / MGI
- cochlear ganglion degeneration / MGI
- increased liver weight / MGI
- increased kidney weight / MGI
- abnormal utricular macula morphology / MGI
- cochlear hair cell degeneration / MGI
- thin stria vascularis / MGI
- cochlear inner hair cell degeneration / MGI
- cochlear outer hair cell degeneration / MGI
- abnormal thyroid follicle morphology / MGI
- abnormal distortion product otoacoustic emission / MGI
- syndromic hearing loss / MGI
- increased spleen weight / MGI
- renal/urinary system phenotype / MGI
- liver/biliary system phenotype / MGI
- hearing/vestibular/ear phenotype / MGI
- endocrine/exocrine gland phenotype / MGI
- digestive/alimentary phenotype / MGI
- cardiovascular system phenotype / MGI
- absent pinna reflex / MGI
- abnormal olfactory epithelium morphology / MGI
- abnormal salivary gland duct morphology / MGI
- increased or absent threshold for auditory brainstem response / MGI