IMPC phenotypes (gene matching)
C3HeB/FeJ-Otop1ied/Orl
| Status | Available to order |
| EMMA ID | EM:00733 |
| International strain name | C3HeB/FeJ-Otop1ied/Orl |
| Alternative name | Ied1 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Otop1ied |
| Gene/Transgene symbol | Otop1 |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Phenotypic information | Head tilt, balance deficit, altered swimming capacity, otocyst defect in vestibular system. |
| Breeding history | Inbred at F5. |
| References |
|
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- impaired coordination / MGI
- abnormal posture / MGI
- impaired swimming / MGI
- impaired righting response / MGI
- abnormal motor capabilities/coordination/movement / MGI
- decreased vertical activity / MGI
- abnormal vestibular ganglion morphology / MGI
- absent otoliths / MGI
- abnormal vestibular system physiology / MGI
- absent linear vestibular evoked potential / MGI
- head tilt / MGI
- hearing/vestibular/ear phenotype / MGI
Literature references
- Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1.;Besson Vanessa, Nalesso Valérie, Herpin Alexandre, Bizot Jean-Charles, Messaddeq Nadia, Romand Raymond, Puech Anne, Blanquet Véronique, Hérault Yann, ;2005;Biology of the cell;97;787-98; 15730345