IMPC phenotypes (gene matching)
C3HeB/FeJ-Otop1ied/Orl
| Status | Available to order |
| EMMA ID | EM:00733 |
| Citation information | RRID:IMSR_EM:00733 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Otop1ied/Orl |
| Alternative name | Ied1 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Otop1ied |
| Gene/Transgene symbol | Otop1 |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Phenotypic information | Head tilt, balance deficit, altered swimming capacity, otocyst defect in vestibular system. |
| Breeding history | Inbred at F5. |
| References |
|
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- impaired coordination / MGI
- abnormal posture / MGI
- impaired swimming / MGI
- impaired righting response / MGI
- abnormal motor capabilities/coordination/movement / MGI
- decreased vertical activity / MGI
- abnormal vestibular ganglion morphology / MGI
- absent otoliths / MGI
- abnormal vestibular system physiology / MGI
- absent linear vestibular evoked potential / MGI
- head tilt / MGI
- hearing/vestibular/ear phenotype / MGI
Literature references
- Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1.;Besson Vanessa, Nalesso Valérie, Herpin Alexandre, Bizot Jean-Charles, Messaddeq Nadia, Romand Raymond, Puech Anne, Blanquet Véronique, Hérault Yann, ;2005;Biology of the cell;97;787-98; 15730345