- abnormal cell morphology / MGI
- abnormal dentate gyrus morphology / MGI
- dilated lateral ventricles / MGI
- reduced male fertility / MGI
- decreased litter size / MGI
- no abnormal phenotype detected / MGI
- asthenozoospermia / MGI
- oligozoospermia / MGI
- increased thigmotaxis / MGI
- decreased testis weight / MGI
- decreased epididymis weight / MGI
- behavior/neurological phenotype / MGI
- hematopoietic system phenotype / MGI
- teratozoospermia / MGI
- abnormal cell physiology / MGI
- abnormal male germ cell apoptosis / MGI
- short sperm flagellum / MGI
- abnormal sperm annulus morphology / MGI
- mortality/aging / MGI
- integument phenotype / MGI
STOCK Atat1tm1.1Phep/Cnrm
Status | Available to order |
EMMA ID | EM:07148 |
International strain name | STOCK Atat1tm1.1Phep/Cnrm |
Alternative name | Atat1 Flx |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Atat1tm1.1Phep |
Gene/Transgene symbol | Atat1 |
Information from provider
Provider | Paul Heppenstall |
Provider affiliation | Adriano Buzzati-Traverso Campus, EMBL Monterotondo |
Genetic information | Exons 1-6 of the Atat1 allele are flanked with loxP sites that enable conditional mutagenesis. FRT site is 3' of the 3' loxP site. |
Phenotypic information | No detected phenotypes. |
References |
|
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
Literature references
- αTAT1 is the major α-tubulin acetyltransferase in mice.;Kalebic Nereo, Sorrentino Simona, Perlas Emerald, Bolasco Giulia, Martinez Concepcion, Heppenstall Paul A, ;2013;Nature communications;4;1962; 23748901
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