IMPC phenotypes (gene matching)
- abnormal reproductive system morphology / IMPC
STOCK Nebltm1(cre)Chen/Cnrm
| Status | Available to order |
| EMMA ID | EM:07146 |
| International strain name | STOCK Nebltm1(cre)Chen/Cnrm |
| Alternative name | Nebulette knockout mouse |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Nebltm1(cre)Chen |
| Gene/Transgene symbol | Nebl |
Information from provider
| Provider | Marie-Louise Bang |
| Provider affiliation | University of California San Diego |
| Genetic information | Nebulette knockout mouse |
| Phenotypic information | Nebulette knockout mice have no obvious cardiac phenotype |
| Breeding history | The chimeric mice were crossed with Black Swiss mice to achieve germline transmission and were subsequently crossed once more with Black Swiss mice. After that they were kept in the mixed background. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.;Mastrototaro Giuseppina, Liang Xingqun, Li Xiaodong, Carullo Pierluigi, Piroddi Nicoletta, Tesi Chiara, Gu Yusu, Dalton Nancy D, Peterson Kirk L, Poggesi Corrado, Sheikh Farah, Chen Ju, Bang Marie-Louise, ;2015;Cardiovascular research;107;216-25; 25987543