IMPC phenotypes (allele matching)
C57BL/6N-Atm1Brd Srrm4tm1e(EUCOMM)Wtsi/WtsiCnrm
| Status | Available to order |
| EMMA ID | EM:07126 |
| International strain name | C57BL/6N-Atm1Brd Srrm4tm1e(EUCOMM)Wtsi/WtsiCnrm |
| Alternative name | EPD0538_3_A07 |
| Strain type | Targeted Mutant Strains : Targeted Non-conditional |
| Allele/Transgene symbol | Srrm4tm1e(EUCOMM)Wtsi |
| Gene/Transgene symbol | Srrm4 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0538_3_A07. For further details on the construction of this clone see the page at the IMPC portal. The targeted allele has lost the 3' loxP site. These mutations cannot be converted into conditional alleles. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal inner ear morphology / MGI
- tremors / MGI
- abnormal corpus callosum morphology / MGI
- abnormal stratification in cerebral cortex / MGI
- circling / MGI
- abnormal pinna reflex / MGI
- impaired balance / MGI
- cyanosis / MGI
- respiratory distress / MGI
- deafness / MGI
- abnormal innervation / MGI
- abnormal vestibular hair cell morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal axon guidance / MGI
- no phenotypic analysis / MGI
- premature neuronal precursor differentiation / MGI
- abnormal axon extension / MGI
- abnormal pillar cell morphology / MGI
- abnormal crista ampullaris morphology / MGI
- abnormal embryonic/fetal subventricular zone morphology / MGI
- absent pillar cells / MGI
- decreased vestibular hair cell number / MGI
- abnormal utricular macula morphology / MGI
- utricular macular degeneration / MGI
- abnormal cochlear inner hair cell morphology / MGI
- decreased cochlear inner hair cell number / MGI
- absent cochlear inner hair cells / MGI
- cochlear inner hair cell degeneration / MGI
- absent vestibular hair cell stereocilia / MGI
- abnormal cochlear hair cell development / MGI
- abnormal distortion product otoacoustic emission / MGI
- decreased neuronal precursor cell number / MGI
- head tilt / MGI
- head tossing / MGI
- abnormal hearing electrophysiology / MGI
- abnormal otoacoustic response / MGI
- abnormal neurite morphology / MGI
- decreased survivor rate / MGI
- decreased neuron number / MGI
- neonatal lethality, incomplete penetrance / MGI
- increased or absent threshold for auditory brainstem response / MGI
- abnormal phrenic nerve innervation pattern to diaphragm / MGI