MGI phenotypes (gene matching)
B6N.Cg-Piwil2tm2.1Doca/Cnrm
| Status | Available to order |
| EMMA ID | EM:07097 |
| Citation information | RRID:IMSR_EM:07097 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N.Cg-Piwil2tm2.1Doca/Cnrm |
| Alternative name | MiliFlox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Piwil2tm2.1Doca |
| Gene/Transgene symbol | Piwil2 |
Information from provider
| Provider | Donal O'Carroll |
| Provider affiliation | Mouse Biology Unit, European Molecular Biology Laboratory |
| Genetic information | Exon 21 was flanked by two loxP sites for the formation of a null allele through Cre recombination. One Frt site is present between exon 21 and the loxP site at the 3' end of this exon. |
| Phenotypic information | No phenotype unless crossed with a specific cre mouse line. |
| Breeding history | The mouse was backcrossed 8 times with C57BL/6N mice. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.;Di Giacomo Monica, Comazzetto Stefano, Saini Harpreet, De Fazio Serena, Carrieri Claudia, Morgan Marcos, Vasiliauskaite Lina, Benes Vladimir, Enright Anton J, O'Carroll Dónal, ;2013;Molecular cell;50;601-8; 23706823