B6.Cg-Tg(Rax-cre)1Zkoz/Ph
| Status | Available to order |
| EMMA ID | EM:06880 |
| Citation information | RRID:IMSR_EM:06880 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Rax-cre)1Zkoz/Ph |
| Alternative name | C57BL/6-Tg(mRx-Cre)1Zkoz |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Rax-cre)1Zkoz |
| Gene/Transgene symbol | Tg(Rax-cre)1Zkoz |
Information from provider
| Provider | Zbynek Kozmik |
| Provider affiliation | Dept. of Transcriptional Regulation, Institute of Molecular Genetics AS CR, v.v.i. |
| Genetic information | A BAC clone (RP24-82D21) containing 200kb covering the mouse Rx locus was modified by insertion of Cre recombinase into the first ATG of the Rx gene. The Cre-inserted BAC was used for pronuclear injection. |
| Phenotypic information | Cre recombinase is expressed in the pattern corresponding to the endogenous Rx gene: in optic vesicles and ventral forebrain from E9.0 embryos and later in retina and ventral forebrain. |
| Breeding history | This mouse strain was crossed 4x to C57BL/6NCrl. Breeding takes place only by crossing WT x tg mice. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6NTac males |
| Breeding at archiving centre | Transgenic males were put into breeding to generate "proven breeders". Males were used for sperm freezing and for IVF to generate embryos for freezing. |
| Stage of embryos | 2-cell |