- abnormal adipose tissue distribution / MGI
- abnormal intestine morphology / MGI
- abnormal liver morphology / MGI
- thick dermal layer / MGI
- edema / MGI
- abnormal lymphatic vessel morphology / MGI
- postnatal lethality / MGI
- extremity edema / MGI
- lymphedema / MGI
- abnormal lymph circulation / MGI
- reproductive system phenotype / MGI
- abnormal lymphangiogenesis / MGI
- chylous ascites / MGI
- cardiovascular system phenotype / MGI
- absent lymphatic vessels / MGI
- embryonic growth retardation / MGI
- prenatal lethality, complete penetrance / MGI
C3H101H-Flt4Chy/H
Status | Available to order |
EMMA ID | EM:00068 |
International strain name | C3H101H-Flt4Chy/H |
Alternative name | chylous ascites |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | Flt4Chy |
Gene/Transgene symbol | Flt4 |
Information from provider
Provider | Martin FRAY |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Phenotypic information | Milky abdomen shortly after birth; (abdomen, feet) chylous ascites. From crosses of 3H1 females to heterozygous males, approx. 40% of the offspring exhibited the milky abdomen phenotype; of these, about 50% survived through to weaning age. |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Tetralogy of Fallot / Orphanet_3303
- Milroy disease / Orphanet_79452
MGI phenotypes (allele matching)
MGI phenotypes (gene matching)
- abnormal adipose tissue distribution / MGI
- abnormal vascular development / MGI
- abnormal intestine morphology / MGI
- abnormal liver morphology / MGI
- thick dermal layer / MGI
- pale yolk sac / MGI
- edema / MGI
- pericardial edema / MGI
- abnormal lymphatic vessel morphology / MGI
- postnatal lethality / MGI
- no abnormal phenotype detected / MGI
- hydrops fetalis / MGI
- no phenotypic analysis / MGI
- extremity edema / MGI
- lymphedema / MGI
- abnormal lymph circulation / MGI
- embryonic growth retardation / MGI
- abnormal vitelline vascular remodeling / MGI
- abnormal anterior cardinal vein morphology / MGI
- abnormal dorsal aorta morphology / MGI
- hemopericardium / MGI
- cardiovascular system phenotype / MGI
- reproductive system phenotype / MGI
- abnormal lymphangiogenesis / MGI
- absent lymphatic vessels / MGI
- neonatal lethality, complete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- chylous ascites / MGI
- abnormal perineural vascular plexus morphology / MGI
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