MGI phenotypes (gene matching)
129S5-Cochtm1Wtsi/WtsiCnrm
| Status | Available to order |
| EMMA ID | EM:06298 |
| International strain name | 129S5-Cochtm1Wtsi/WtsiCnrm |
| Alternative name | CHOCHO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Cochtm1Wtsi |
| Gene/Transgene symbol | Coch |
Information from provider
| Provider | Karen Steel |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Additional owner | Lorraine Everett and Ilona Zvetkova produced this line while employed by WTSI. |
| Genetic information | This line carries a targeted mutation disrupting the Coch gene. |
| Phenotypic information | This mutant may show hearing loss, but it has not been well-studied yet. |
| Breeding history | Believed to have been maintained on a pure 129S5 genetic background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant non-syndromic sensorineural deafness type DFNA / Orphanet_90635