MGI phenotypes (gene matching)
129S5-Cochtm1Wtsi/WtsiCnrm
| Status | Available to order |
| EMMA ID | EM:06298 |
| Citation information | RRID:IMSR_EM:06298 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | 129S5-Cochtm1Wtsi/WtsiCnrm |
| Alternative name | CHOCHO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Cochtm1Wtsi |
| Gene/Transgene symbol | Coch |
Information from provider
| Provider | Karen Steel |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Additional owner | Lorraine Everett and Ilona Zvetkova produced this line while employed by WTSI. |
| Genetic information | This line carries a targeted mutation disrupting the Coch gene. |
| Phenotypic information | This mutant may show hearing loss, but it has not been well-studied yet. |
| Breeding history | Believed to have been maintained on a pure 129S5 genetic background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant non-syndromic sensorineural deafness type DFNA / Orphanet_90635