B6.FVB-Tg(Cdx1-cre)23Kem/Ieg

Status

Available to order

EMMA IDEM:06272
International strain nameB6.FVB-Tg(Cdx1-cre)23Kem/Ieg
Alternative nameCdx1::Cre
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Cdx1-cre)23Kem
Gene/Transgene symbolTg(Cdx1-cre)23Kem

Information from provider

ProviderAndreas Hierholzer
Provider affiliationMolecular Embryology, Max-Planck-Institute for Immunobiology and Epigenetics
Genetic informationTransgene contains 3.6kb of the Cdx1 promoter to drive cre recombinase expression in the Cdx1 expression domain.
Phenotypic informationNo phenotype.
Breeding historyThe line has been backcrossed to C57BL/6 mice at least for 15 generations.
References
  • Cdx1::Cre allele for gene analysis in the extraembryonic ectoderm and the three germ layers of mice at mid-gastrulation.;Hierholzer Andreas, Kemler Rolf, ;2009;Genesis (New York, N.Y. : 2000);47;204-9; 19241391
  • Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos.;Hierholzer Andreas, Kemler Rolf, ;2010;Developmental dynamics : an official publication of the American Association of Anatomists;239;191-9; 19705445
  • Differential requirements for β-catenin during mouse development.;Rudloff Stefan, Kemler Rolf, ;2012;Development (Cambridge, England);139;3711-21; 22991437
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6J

Literature references

  • Cdx1::Cre allele for gene analysis in the extraembryonic ectoderm and the three germ layers of mice at mid-gastrulation.;Hierholzer Andreas, Kemler Rolf, ;2009;Genesis (New York, N.Y. : 2000);47;204-9; 19241391
  • Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos.;Hierholzer Andreas, Kemler Rolf, ;2010;Developmental dynamics : an official publication of the American Association of Anatomists;239;191-9; 19705445
  • Differential requirements for β-catenin during mouse development.;Rudloff Stefan, Kemler Rolf, ;2012;Development (Cambridge, England);139;3711-21; 22991437

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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