B6.FVB-Tg(Cdx1-cre)23Kem/Ieg

Status	Available to order
EMMA ID	EM:06272
Citation information	RRID:IMSR_EM:06272 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6.FVB-Tg(Cdx1-cre)23Kem/Ieg
Alternative name	Cdx1::Cre
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Cdx1-cre)23Kem
Gene/Transgene symbol	Tg(Cdx1-cre)23Kem

Information from provider

Provider	Andreas Hierholzer
Provider affiliation	Molecular Embryology, Max-Planck-Institute for Immunobiology and Epigenetics
Genetic information	Transgene contains 3.6kb of the Cdx1 promoter to drive cre recombinase expression in the Cdx1 expression domain.
Phenotypic information	No phenotype.
Breeding history	The line has been backcrossed to C57BL/6 mice at least for 15 generations.
References	Cdx1::Cre allele for gene analysis in the extraembryonic ectoderm and the three germ layers of mice at mid-gastrulation.;Hierholzer Andreas, Kemler Rolf, ;2009;Genesis (New York, N.Y. : 2000);47;204-9; 19241391 Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos.;Hierholzer Andreas, Kemler Rolf, ;2010;Developmental dynamics : an official publication of the American Association of Anatomists;239;191-9; 19705445 Differential requirements for β-catenin during mouse development.;Rudloff Stefan, Kemler Rolf, ;2012;Development (Cambridge, England);139;3711-21; 22991437
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archiving	heterozygous C57BL/6J males

Literature references

Cdx1::Cre allele for gene analysis in the extraembryonic ectoderm and the three germ layers of mice at mid-gastrulation.;Hierholzer Andreas, Kemler Rolf, ;2009;Genesis (New York, N.Y. : 2000);47;204-9; 19241391
Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos.;Hierholzer Andreas, Kemler Rolf, ;2010;Developmental dynamics : an official publication of the American Association of Anatomists;239;191-9; 19705445
Differential requirements for β-catenin during mouse development.;Rudloff Stefan, Kemler Rolf, ;2012;Development (Cambridge, England);139;3711-21; 22991437

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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