- increased circulating calcium level / IMPC
- increased circulating insulin level / IMPC
- increased heart weight / IMPC
- increased circulating alkaline phosphatase level / IMPC
- decreased circulating chloride level / IMPC
- fusion of vertebral arches / IMPC
- improved glucose tolerance / IMPC
- increased blood urea nitrogen level / IMPC
C57BL/6N-Atm1Brd Slc25a4tm1a(EUCOMM)Wtsi/WtsiH
Status | Available to order |
EMMA ID | EM:06192 |
International strain name | C57BL/6N-Atm1Brd Slc25a4tm1a(EUCOMM)Wtsi/WtsiH |
Alternative name | EPD0369_5_A05 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Slc25a4tm1a(EUCOMM)Wtsi |
Gene/Transgene symbol | Slc25a4 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0369_5_A05. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | homozygous C57BL/6NTac |
Breeding at archiving centre | Frozen samples received. No breeding at archiving centre. Due to the possible presence of C57BL/6N-Atm1Brd/a, may produce agouti pups. |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Congenital cataract-hypertrophic cardiomyopathy-mitochondrial myopathy syndrome / Orphanet_1369
- Autosomal dominant progressive external ophthalmoplegia / Orphanet_254892
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased blood urea nitrogen level / IMPC
- decreased circulating chloride level / IMPC
- fusion of vertebral arches / IMPC
- increased circulating calcium level / IMPC
- increased heart weight / IMPC
- increased circulating insulin level / IMPC
- improved glucose tolerance / IMPC
- increased circulating alkaline phosphatase level / IMPC
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