MGI phenotypes (allele matching)
B6.129S7-Vax2tm1Sba/Cnrm
| Status | Available to order |
| EMMA ID | EM:00584 |
| Citation information | RRID:IMSR_EM:00584 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S7-Vax2tm1Sba/Cnrm |
| Alternative name | 129/C57BL6/Vax2-/- |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Vax2tm1Sba |
| Gene/Transgene symbol | Vax2 |
Information from provider
| Provider | Sandro Banfi |
| Provider affiliation | Telethon Institute of Genetics and Medicine (TIGEM) |
| Genetic information | The mutation has been obtained by homologous recombination by deleting the second coding exon of the Vax2 gene. |
| Phenotypic information | Alteration of the eye, dorso-ventral axis, incompletely penetrant eye coloboma. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma.;Barbieri Anna Maria, Broccoli Vania, Bovolenta Paola, Alfano Giovanna, Marchitiello Anna, Mocchetti Cristina, Crippa Luca, Bulfone Alessandro, Marigo Valeria, Ballabio Andrea, Banfi Sandro, ;2002;Development (Cambridge, England);129;805-13; 11830579