- abnormal frontal bone morphology / MGI
- midline facial cleft / MGI
- abnormal scapula morphology / MGI
- abnormal craniofacial morphology / MGI
- abnormal head morphology / MGI
- increased cranium width / MGI
- abnormal carpal bone morphology / MGI
- abnormal hindlimb morphology / MGI
- abnormal tibia morphology / MGI
- polydactyly / MGI
- abnormal autopod morphology / MGI
- abnormal foot pad morphology / MGI
- clubfoot / MGI
- kinked tail / MGI
- thick tail / MGI
- abnormal diencephalon morphology / MGI
- cranioschisis / MGI
- decreased body weight / MGI
- decreased body size / MGI
- hunched posture / MGI
- decreased embryo size / MGI
- edema / MGI
- hydroencephaly / MGI
- infertility / MGI
- male infertility / MGI
- female infertility / MGI
- abnormal estrous cycle / MGI
- decreased litter size / MGI
- premature death / MGI
- abnormal eye morphology / MGI
- abnormal limb morphology / MGI
- abnormal digit morphology / MGI
- abnormal tail morphology / MGI
- abnormal fibula morphology / MGI
- delayed vaginal opening / MGI
- oligozoospermia / MGI
- short tibia / MGI
- abnormal long bone morphology / MGI
- polysyndactyly / MGI
- scapular bone foramen / MGI
- bowed tibia / MGI
- bowed ulna / MGI
- bowed fibula / MGI
- bowed radius / MGI
- broad limb buds / MGI
- increased lumbar vertebrae number / MGI
- decreased length of long bones / MGI
- decreased testis weight / MGI
- abnormal tarsal bone morphology / MGI
- limbs/digits/tail phenotype / MGI
- craniofacial phenotype / MGI
- abnormal skeleton morphology / MGI
- abnormal thoracic cage shape / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- Wormian bones / MGI
- broad snout / MGI
- wide sagittal suture / MGI
- abnormal anterior fontanelle morphology / MGI
- wide metopic suture / MGI
C3H101H-Dbf/H
Status | Available to order |
EMMA ID | EM:00058 |
International strain name | C3H101H-Dbf/H |
Alternative name | Doublefoot, Dbf |
Strain type | Spontaneous |
Allele/Transgene symbol | Dbf |
Gene/Transgene symbol | Dbf |
Information from provider
Provider | Mary Lyon |
Provider affiliation | MRC Mammalian Genetics Unit |
Genetic information | This strain carries a spontaneous mutation which arose in the (C3H/HeH x 101/H)F1 stock. |
Phenotypic information | Mice carrying the Dbf mutation have numerous extra toes on all feet. |
References |
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Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
MGI phenotypes (gene matching)
Literature references
- Doublefoot: a new mouse mutant affecting development of limbs and head.;Lyon M F, Quinney R, Glenister P H, Kerscher S, Guillot P, Boyd Y, ;1996;Genetical research;68;221-31; 9062079
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