MGI phenotypes (allele matching)
- decreased body weight / MGI
C57BL/6N-Atm1Brd Cc2d2atm1a(EUCOMM)Wtsi/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:05701 |
| International strain name | C57BL/6N-Atm1Brd Cc2d2atm1a(EUCOMM)Wtsi/WtsiIeg |
| Alternative name | EPD0381_1_A04 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Cc2d2atm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Cc2d2a |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0381_1_A04. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Joubert syndrome with hepatic defect / Orphanet_1454
- Joubert syndrome with oculorenal defect / Orphanet_2318
- Meckel syndrome / Orphanet_564
MGI phenotypes (gene matching)
- cleft palate / MGI
- double outlet right ventricle / MGI
- polydactyly / MGI
- dextrocardia / MGI
- exencephaly / MGI
- incomplete rostral neuropore closure / MGI
- decreased body weight / MGI
- anophthalmia / MGI
- microphthalmia / MGI
- abnormal retina morphology / MGI
- abnormal embryo development / MGI
- decreased embryo size / MGI
- abnormal left-right axis patterning / MGI
- postnatal growth retardation / MGI
- hydroencephaly / MGI
- hemorrhage / MGI
- abnormal neural tube morphology / MGI
- abnormal tracheal ciliated epithelium morphology / MGI
- persistent truncus arteriosis / MGI
- situs inversus / MGI
- kidney cysts / MGI
- abnormal photoreceptor outer segment morphology / MGI
- abnormal photoreceptor inner segment morphology / MGI
- abnormal retinal outer nuclear layer morphology / MGI
- duplex kidney / MGI
- abnormal primitive node morphology / MGI
- heterotaxia / MGI
- abnormal cochlear hair cell stereociliary bundle morphology / MGI
- holoprosencephaly / MGI
- lethargy / MGI
- abnormal rostral-caudal axis patterning / MGI
- cellular phenotype / MGI
- abnormal eye electrophysiology / MGI
- tricuspid valve atresia / MGI
- pulmonary valve atresia / MGI
- polycystic kidney / MGI
- abnormal vesicle-mediated transport / MGI
- preaxial polydactyly / MGI
- focal dorsal hair loss / MGI
- ventricular septal defect / MGI
- common atrium / MGI
- atrioventricular septal defect / MGI
- complete atrioventricular septal defect / MGI
- muscular ventricular septal defect / MGI
- prenatal growth retardation / MGI
- decreased respiratory motile cilia number / MGI
- abnormal kinocilium morphology / MGI
- abnormal renal tubule epithelial cell primary cilium morphology / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- superior-inferior ventricles / MGI
- biventricular, discordant atrioventricular connection / MGI
- double outlet right ventricle with atrioventricular septal defect / MGI
- decreased embryonic cilium number / MGI
- abnormal primary cilium morphology / MGI
- abnormal nonmotile primary cilium morphology / MGI
- decreased embryonic neuroepithelium primary cilium number / MGI