- abnormal inner ear morphology / MGI
- absent semicircular canals / MGI
- abnormal cartilage morphology / MGI
- abnormal cranium morphology / MGI
- decreased brain size / MGI
- increased inferior colliculus size / MGI
- abnormal cerebral cortex morphology / MGI
- abnormal third ventricle morphology / MGI
- abnormal cerebellar foliation / MGI
- abnormal midbrain morphology / MGI
- increased superior colliculus size / MGI
- abnormal trigeminal V mesencephalic nucleus morphology / MGI
- abnormal telencephalon development / MGI
- convulsive seizures / MGI
- nonconvulsive seizures / MGI
- small ovary / MGI
- abnormal ovarian folliculogenesis / MGI
- small testis / MGI
- arrest of spermatogenesis / MGI
- decreased body weight / MGI
- abnormal lens morphology / MGI
- abnormal iris morphology / MGI
- retina hyperplasia / MGI
- absent lacrimal glands / MGI
- circling / MGI
- postnatal growth retardation / MGI
- abnormal pituitary secretion / MGI
- seizures / MGI
- premature death / MGI
- abnormal eye morphology / MGI
- decreased brain weight / MGI
- abnormal seminiferous tubule morphology / MGI
- delayed fertility / MGI
- head shaking / MGI
- decreased circulating testosterone level / MGI
- decreased superior colliculus size / MGI
- absent lateral semicircular canal / MGI
- nervous system phenotype / MGI
- abnormal nervous system morphology / MGI
- abnormal orbitosphenoid bone morphology / MGI
- abnormal eye anterior chamber morphology / MGI
- hearing/vestibular/ear phenotype / MGI
- behavior/neurological phenotype / MGI
- abnormal vestibular saccule morphology / MGI
- abnormal utricle morphology / MGI
- small hippocampus / MGI
- absent Harderian gland / MGI
- decreased inferior colliculus size / MGI
- meteorism / MGI
- mortality/aging / MGI
- postnatal lethality, incomplete penetrance / MGI
- neonatal lethality, complete penetrance / MGI
- increased cornea thickness / MGI
- decreased midbrain size / MGI
- absent ciliary process / MGI
- increased cerebellar foliation / MGI
STOCK Otx1tm5Asim/Cnrm
Status | Available to order |
EMMA ID | EM:05638 |
International strain name | STOCK Otx1tm5Asim/Cnrm |
Alternative name | Otx1-Flox |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Otx1tm5Asim |
Gene/Transgene symbol | Otx1 |
Information from provider
Provider | Antonio Simeone |
Provider affiliation | Ceinge Biotecnologie Avanzate |
Genetic information | The Otx1 exon 2 is flanked by loxP sites. |
Phenotypic information | No phenotype. |
References | None available |
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | yes |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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