MGI phenotypes (allele matching)
B6.Cg-Piwil1tm1.2Embrp/Cnrm
| Status | Available to order |
| EMMA ID | EM:05594 |
| Citation information | RRID:IMSR_EM:05594 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Piwil1tm1.2Embrp/Cnrm |
| Alternative name | Miwi KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Piwil1tm1.2Embrp |
| Gene/Transgene symbol | Piwil1 |
Information from provider
| Provider | Ramesh PILLAI |
| Provider affiliation | Mouse Biology Unit, European Molecular Biology Laboratory |
| Genetic information | Piwil1 (Miwi) knock-out allele. Removes exons 16 and 17. |
| Phenotypic information | Only males show infertility. Block in spermatogenesis at round spermatids. |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.;Reuter Michael, Berninger Philipp, Chuma Shinichiro, Shah Hardik, Hosokawa Mihoko, Funaya Charlotta, Antony Claude, Sachidanandam Ravi, Pillai Ramesh S, ;2011;Nature;480;264-7; 22121019