MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
C57BL/6N-Tmem45btm1.2Arte/Ieg
| Status | Available to order |
| EMMA ID | EM:05498 |
| International strain name | C57BL/6N-Tmem45btm1.2Arte/Ieg |
| Alternative name | TMEM45B KO conv |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Tmem45btm1.2 |
| Gene/Transgene symbol | Tmem45b |
Information from provider
| Provider | Helmholtz Zentrum Muenchen |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
| Genetic information | Exons 3-5 have been flanked by loxP sites, as their genetic ablation should result in loss of function by deletion of most of the open reading frame and generation of a frameshift (see EMMA strain EM:05499). The constitutive knock-out mutation has been obtained by in vivo cre recombinase-mediated deletion. |
| Phenotypic information | TO BE PROVIDED |
| Breeding history | Targeting performed in C57BL/6N ES cells and confirmed by Southern blotting. Tmem45b floxed mice were crossed to C57BL/6N-Gt(ROSA)26Sortm16(cre)Arte mice to obtain the Tmem45b null allele. Maintained on C57BL/6N background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6NTac, wild-type C57BL/6N |
| Stage of embryos | 2-cell |