C57BL/6N-Cd200tm1a(KOMP)Wtsi/H
Status | Available to order |
EMMA ID | EM:05361 |
International strain name | C57BL/6N-Cd200tm1a(KOMP)Wtsi/H |
Alternative name | EPD0282_1_A03 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Cd200tm1a(KOMP)Wtsi |
Gene/Transgene symbol | Cd200 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from KOMP ES clone EPD0282_1_A03. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac |
Breeding at archiving centre | Chimeras were mated to C57BL/6N Tac USA and maintained on this background thereafter. |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- abnormal microglial cell morphology / MGI
- enlarged lymph nodes / MGI
- abnormal immune system physiology / MGI
- abnormal lymph node morphology / MGI
- abnormal macrophage physiology / MGI
- abnormal immune system organ morphology / MGI
- abnormal microglial cell physiology / MGI
- increased susceptibility to induced arthritis / MGI
- increased susceptibility to experimental autoimmune encephalomyelitis / MGI
- increased susceptibility to experimental autoimmune uveoretinitis / MGI
- increased macrophage cell number / MGI
- increased apoptosis / MGI
- increased spleen red pulp amount / MGI
- abnormal cytokine level / MGI
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