B6;D2-Tg(Mlana-cre)5Bee/Orl
| Status | Available to order |
| EMMA ID | EM:05247 |
| Citation information | RRID:IMSR_EM:05247 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;D2-Tg(Mlana-cre)5Bee/Orl |
| Alternative name | Mart-1::Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Mlana-cre)5Bee |
| Gene/Transgene symbol | Tg(Mlana-cre)5Bee |
Information from provider
| Provider | Friedrich Beermann |
| Provider affiliation | EPFL SV ISREC |
| Genetic information | A MART-1 BAC was modified by homologous recombination in bacteria and contains a Cre recombinase allowing for Cre recombinase expression driven by regulatory sequences of the MART-1/Mlana gene. |
| Phenotypic information | This is a Cre-expressing line which allows Cre expression in melanocytes and in the retinal pigment epithelium. |
| Breeding history | It is currently backcrossed to C57BL/6. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
Literature references
- A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium.;Aydin Iraz T, Beermann Friedrich, ;2011;Genesis (New York, N.Y. : 2000);49;403-9; 21309074
- RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice.;Schouwey K, Aydin I T, Radtke F, Beermann F, ;2011;Oncogene;30;313-22; 20856205