C.Cg-Tg(Tek-cre)1Ywa/Cnbc
| Status | Available to order |
| EMMA ID | EM:05243 |
| International strain name | C.Cg-Tg(Tek-cre)1Ywa/Cnbc |
| Alternative name | Tie2 Cre Balb/c (backcross of Cg-Tg(Tek-cre)1Ywa/J - Jax) |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tek-cre)1Ywa |
| Gene/Transgene symbol | Tg(Tek-cre)1Ywa |
Information from provider
| Provider | Wouter Lamers |
| Provider affiliation | Maastricht University |
| Additional owner | Prof. Masashi Yanagisawa, UT Southwestern Medical Center at Dallas, Texas, U.S.A. |
| Genetic information | This transgene expresses Cre recombinase under the control of a mouse Tek promoter and enhancer. Recombinase activity results in the deletion of loxP flanked targets in the female germline as well as in endothelial cells and hematopoietic cells. Always cross male hemizygotes with female wild types (with respect to the Cre transgene). |
| Phenotypic information | No apparent phenotype. Mice are healthy and fertile. |
| Breeding history | Backcrossed more than 10 times to BALB/c. Bred as hemizygous x wild type. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous BALB/c, wild-type BALB/c |
| Stage of embryos | 2-cell |
Literature references
- Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.;Kisanuki Y Y, Hammer R E, Miyazaki J, Williams S C, Richardson J A, Yanagisawa M, ;2001;Developmental biology;230;230-42; 11161575