IMPC phenotypes (gene matching)
STOCK Gjd4tm1.1Malt/Cnrm
| Status | Available to order |
| EMMA ID | EM:05216 |
| Citation information | RRID:IMSR_EM:05216 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Gjd4tm1.1Malt/Cnrm |
| Alternative name | Cx39KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Gjd4tm1.1Malt |
| Gene/Transgene symbol | Gjd4 |
Information from provider
| Provider | Klaus WILLECKE |
| Provider affiliation | Molekulargenetik, Institut fuer Genetik, Universitaet Bonn |
| Genetic information | The Cx39 (Gjd4) deficient mice were generated by replacing the coding region of the Gjd4 gene with DNA coding for the enhanced green fluorescent protein eGFP. |
| Phenotypic information | No obvious phenotype but connexin 39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. |
| Breeding history | Founder animals were backcrossed to C57BL/6 more than three times (more than 85%). |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle.;von Maltzahn Julia, Wulf Volker, Matern Gabi, Willecke Klaus, ;2011;Experimental cell research;317;1169-78; 21272575