MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
B6;129-Tg(CAG-dre)1Afst/Ieg
| Status | Available to order |
| EMMA ID | EM:05147 |
| International strain name | B6;129-Tg(CAG-dre)1Afst/Ieg |
| Alternative name | CAGGs-Dre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CAG-dre)1Afst |
| Gene/Transgene symbol | Tg(CAG-dre)1Afst |
Information from provider
| Provider | Konstantinos Anastassiadis |
| Provider affiliation | Stem Cell Engineering / Genomics, Center for Regenerative Therapies, Technische Universitaet Dresden |
| Genetic information | The transgenic mouse strain carries the dre recombinase under the control of the ubiquitous CAGGs promoter. |
| Phenotypic information | This is a dre recombinase deleter strain. There is no obvious phenotype observed. |
| Breeding history | Backcrossed to C57BL/6 for at least 4 generations. Inbred for one generation to test for homozygosity. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.;Anastassiadis Konstantinos, Fu Jun, Patsch Christoph, Hu Shengbiao, Weidlich Stefanie, Duerschke Kristin, Buchholz Frank, Edenhofer Frank, Stewart A Francis, ;2009;Disease models & mechanisms;2;508-15; 19692579