MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
B6;129-Tg(CAG-dre)1Afst/Ieg
| Status | Available to order |
| EMMA ID | EM:05147 |
| Citation information | RRID:IMSR_EM:05147 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Tg(CAG-dre)1Afst/Ieg |
| Alternative name | CAGGs-Dre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CAG-dre)1Afst |
| Gene/Transgene symbol | Tg(CAG-dre)1Afst |
Information from provider
| Provider | Konstantinos Anastassiadis |
| Provider affiliation | Stem Cell Engineering / Genomics, Center for Regenerative Therapies, Technische Universitaet Dresden |
| Genetic information | The transgenic mouse strain carries the dre recombinase under the control of the ubiquitous CAGGs promoter. |
| Phenotypic information | This is a dre recombinase deleter strain. There is no obvious phenotype observed. |
| Breeding history | Backcrossed to C57BL/6 for at least 4 generations. Inbred for one generation to test for homozygosity. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.;Anastassiadis Konstantinos, Fu Jun, Patsch Christoph, Hu Shengbiao, Weidlich Stefanie, Duerschke Kristin, Buchholz Frank, Edenhofer Frank, Stewart A Francis, ;2009;Disease models & mechanisms;2;508-15; 19692579